Category Archives: Temperature Indicators

Flexible Industrial Refrigeration Valve Station

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WESTMONT, IL – This HANTEMP Controls Stainless Steel RR Flexible Station is a rugged weld-in
unit which easily installs via two pipe welds. Because the assembly includes separate quarterturn service valves, it is easy to Repair in-place or to Remove the flanged compact Stainless Steel Solenoid Valve or Pressure Regulator. The outlet service valve can be specified as a model QSVE expansion/shut-off valve for liquid modulating control. Rating for this Stainless Steel unit is 800 psig and minimum temperature is -70°F.


HANTEMP Controls is an established manufacturer of Stainless Steel controlled ball valves, float
switches, solenoid valves, pressure regulators and flange unions for industrial refrigeration
systems including ammonia, CO
2, and others. For more information, please visit
www.hantempcontrols.com

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France’s national blood transfusion service, the Établissement Français de Sang (EFS) – interview with Dr Jean-Pierre Zappitelli

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Dr Jean-Pierre Zappitelli is a pharmacologist and biologist, who works as the senior manager of the Aix-en-Provence laboratory of France’s national blood transfusion service, the Établissement Français de Sang (EFS). He discusses his work within the context of managing the cold chain for blood products

How does the EFS laboratory in Aix-en-Provence fit in with the rest of the EFS and how would you describe your work?

The EFS is France’s sole operator of blood transfusions and its work covers the processing of donations of blood, plasma and platelets. The EFS is France’s safety guarantor of the blood transfusion chain, from donor to recipient. It supports the care of over 1 million patients per annum across France and its overseas territories via 132 fixed and some 40,000 mobile donation sites.

pic-1-esf-laboratories-in-alpes-mediterrarnee-regionThe EFS laboratory in Aix-en-Provence is a reception and distribution point of blood products that have been tested post-donation for pathogens and are ready to be used. In 2015, it processed 20,148 units of blood products (17,529 units of red blood cells; 1,148 units of platelets and 1,471 units of plasma) for the care of 3,759 patients.

I’m the Aix-en-Provence laboratory’s senior manager responsible for delivery and distribution of blood products. By “delivery”, we mean blood products for specific named patients, while by “distribution” we mean for unnamed patients, for instance for hospital stock top-ups.

My work involves ensuring firstly that all of the products we receive are safe to use; secondly that while these products are in the laboratory’s care, they are stored correctly; and lastly, that they are correctly labelled and packed when they leave the laboratory.

How does the Aix-en-Provence laboratory manage the cold chain for the blood products in its care?

This is achieved by maintaining and monitoring the temperature in various areas in the laboratory.

Firstly, the ambient temperature in the laboratory itself is maintained at 25°C. We do this because this is the recommended temperature for the products that are used to determine blood type. If for some reason, this temperature level of 25°C is breached, an alarm sounds and dealing with this issue becomes the primary task that is attended to.

pic-2-refrigerator-temperature-monitorSecondly, all units of blood products – platelets, red blood cells and plasma – are all kept in their own designated refrigerators. These all have a temperature indicator on their door, as well as an independent temperature monitor that is linked to an online map of all of the refrigerators in the laboratory, that is updated in real time with a full suite of data analytics.

The laboratory’s refrigerators have a safety feature whereby whenever one is opened and then closed, a magnet is activated and it cannot be opened for one minute in order to restore the correct ambient temperature within it.

Thirdly, all units of blood products come to the laboratory from regional stock in their own type of container with a “thermo-button” temperature data logger that has monitored the ambient temperature within every container we receive. These temperature data logger are checked using a sensor linked to a PC to ensure that the cold chain wasn’t broken prior to reception. (Some other laboratories in the region use RFID data loggers and for these, the crates don’t need to be opened for data monitoring downloads.)

pic-3-thermo-button-temperature-data-logger-and-sensorAlso, all the bags of products in a group of bags are attached together with a self-locking cable tie that can only be removed by cutting it with pliers.

For blood products that leave our laboratory or may be returned, we group these units of blood products with both a self-locking cable tie and a thermo-button temperature data logger.

Lastly, every group of blood product bags is labelled with a tag indicating source, destination, required temperature and a security notice around handling. Also, every bag of blood product has its own barcode allowing for full traceability.

The laboratory also needs to consider how deliveries of bags of blood products are managed and for this we use two systems: either refrigerated vehicles or isothermal padding.

For bags of red blood cells and platelets, plastic crates are used for transportation in refrigerated vehicles. The crates contain the appropriate type of ice-pack to ensure optimal temperature levels within the crates. Also, these let in the cooled refrigerated air within the vehicle to further ensure that the correct temperature is maintained within them.

For deliveries of bags of frozen plasma, air-tight isothermal crates with extra isothermal padding and its appropriate type of ice-pack. Also, all units of frozen plasma are protected with bubble wrap to avoid any breakages during transportation.

Lastly, all crates are labelled with information regarding source, destination, required temperature and a security notice around handling. Naturally, only authorised personnel can open a crate and this too is indicated on every crate.

How does the laboratory manage suspect items?

The main rule we work by is to eliminate all doubt around decision making about a product. Either it is objectively safe to use or it isn’t, and both of these scenarios are backed up by data, or a lack thereof.

pic-4-thermo-button-temperature-data-logger-readout-within-2c-and-6c-rangeUntil we can determine that a suspect unit of product is safe to use, it’s placed in a quarantine refrigerator until its safety has been 100% confirmed. If this can be done, it then is moved to the appropriate refrigerator. If this cannot be done, it’s disposed of by means of incineration.

Also, any such suspect product, which goes on to be disposed of, is fully documented to ensure full traceability.

In the lab, we make sure that the technicians who process the products we process are never in any doubt about what course of action they need to take.

Our safety systems are built to enable any of our processes to stop at any point. There’s simply no room for error. Patients’ lives are at stake.

What are the risks if the cold chain is broken (plus or minus)?

The risks associated with managing the cold chain for blood products underpins all our work.

If the cold chain for a bag of red blood cells is broken, say during transport, and its core temperature rises above 10°C, the risk is that the patient receives a transfusion that is infected by potentially harmful bacteria. And even with minute amounts of bacteria, at temperatures above 10°C bacterial reproduction can be considerable. For a healthy person, this needn’t necessarily be a problem, but for an already weakened sick patient, it can be extremely dangerous. And for temperatures below 2°C, the risk here is that ice crystals will form, thus impairing its oxygenation property.

Similarly, if platelets are stored or transported at temperatures below the specified limit, there is also an inefficiency risk. So if for example these are stored or transported at a temperature of 12°C instead of 24°C, the purpose of the transfusion (to replace platelets further to some chemotherapy therapy) will be adversely affected, which again poses a danger to the patient. And just like red blood cells stored or transported at a temperature above 24°C, the risk is bacterial reproduction is very high.

pic-5-bag-of-frozen-plasma-1For plasma, the risk when the cold chain is breached is that the product will be altered very rapidly. Plasma is an extremely fragile product that must be used within six hours of being unfrozen.

The final risk around managing the cold chain for blood products is around the labelling of each item. This is why we use various identification tools, including unique barcodes on every bag of blood product. During transport for instance, correct labelling ensures the timely and correct delivery of blood products.

When this doesn’t happen, stocks of blood products could be either delivered to the wrong destination, or arrive late, leading to patients not benefiting from them when they need them or a hospital’s stocks running low, or worse running out, which again puts patients at risk. Furthermore, incorrect labelling inevitably leads to unnecessary wastage to eliminate any chance of putting a patient at risk with a potentially unsound product.

Managing these risks is why for every unit of blood product, there has to be absolute certainty regarding where it’s come from and what its destination is. There’s no room for any grey areas in our work. We only work with 100% certainty around the safety protocols for the blood products we process.

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Ginny Paton

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Ginny Paton MD at House PR in London has done an interview with Gorkana:

Her website is here ginnypaton.co.uk and here ginnypaton.com

Ginny Paton on the social media platforms: http://ginnypaton.co.uk/about/

Extract:

Ginny Paton, MD at House PR, on winning a new client via Twitter, why she’d love to reinvent the Post Office and wanting to schmooze with Robert Peston.

When not in the office you’ll mostly find me… At home with the kids, generally in goal having a ball kicked at me.

Working in PR is… Great fun – and never boring. We get to be involved in all the best bits of our clients’ brand plans. There for all the exciting stuff, like new product launches, anniversaries, ambassador programmes, announcements. And we probably get to duck some of the more mundane bits of our clients’ roles.

Which social media platform has changed your life? Probably Twitter, but I think they all have in different ways. The first time we won a new client via Twitter was a great moment for the agency, and cemented its power commercially for us.

If I could breathe new life into a brand, it would be… The Post Office. Previously much loved and relied upon. There is a huge amount of equity in the brand and it still has a place on the high street and in all our hearts. But reinvention is critical; it needs to modernise, keep up and embrace new digital opportunities.

The most important lesson PR has taught me… Say yes to things – you never know where opportunities will lead you. Particularly at a junior level – say yes to everything, unless there is a very good reason not to. That, and be very careful about who is listening! –

See more at: http://gorkana.com/news/corporate-and-financial/behind-the-headlines/behind-the-headlines-with-ginny-paton/#sthash.ubz51fPC.dpuf

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RS Components introduces Timestrip indicators for convenient asset monitoring and maintenance

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Smart chemistry provides accurate, intuitive, at-a-glance time or time/temperature alerts in a convenient single-use label

OXFORD, UK, July, 2015 RS Components (RS), the trading brand of Electrocomponents plc (LSE:ECM), the global distributor for engineers, has introduced Timestrip time lapse indicators which are visual reminders for timely replacement or servicing and Timestrip PLUS temperature-threshold indicators, which enable convenient and cost-effective monitoring of temperature sensitive perishables.

Patent protected Timestrip time lapse indicators are activated with finger pressure and fixed like a label to the item being monitored. A red colour moves irreversibly against a scale to reach the end when the specified duration expires. 1, 3, 6, and 12-month versions are available, accurate to within ±15% (when used at room temperature), making them ideal for numerous professional and domestic applications. These include simple visual reminders to replace filters or other components in accordance with manufacturer-recommended cycles, or to perform regular maintenance such as heater descaling, inspection of electrical appliances, or servicing of industrial equipment.

Timestrip PLUS temperature-threshold indicators irreversibly show the length of time an item has been exposed above a pre-set temperature threshold. They are ideal for verifying compliance with regulated standards and are used widely for monitoring products whose quality or fitness for use is affected by excess temperature such as pharmaceuticals, perishables such as foodstuffs, and industrial or laboratory chemicals.  Temperature and time indications are accurate to within ±1°C and ±15% respectively.  They are inert until activated and each unit has a unique serial code, which helps manage large numbers of assets. Thresholds of 8C, 10C, 25C and 30C are available.

Compared to alternatives such as written maintenance sheets or electronic reminders, Timestrip indicators are direct, intuitive, and provide an instantaneous at-a-glance indication when action is due or if storage conditions have been breached. They are splashproof, can be stored unused at room temperature, and can be self-affixed to individual products or on packs or pallets.  These compelling and cost-effective indicators support efforts to maximise product quality or improve the performance and reliability of a wide range of equipment, resulting in better end-user experiences.

-Ends-

About RS Components

RS Components and Allied Electronics are the trading brands of Electrocomponents plc, the global distributor for engineers. With operations in 32 countries, we offer more than 500,000 products through the internet, catalogues and at trade counters to over one million customers, shipping around 44,000 parcels a day. Our products, sourced from 2,500 leading suppliers, include electronic components, electrical, automation and control, and test and measurement equipment, and engineering tools and consumables.

Electrocomponents is listed on the London Stock Exchange and in the last financial year ended 31 March 2015 had revenues of £1.27bn.

For more information, please visit the website at www.rs-online.com.

Editorial Contacts:                                                            

Lisa Townsend

PR Manager – EMEA

RS Components

lisa.townsend@rs-components.com

+44 (0)1536 209026

Joanne Youson
Product Marketing PR Manager
RS Components
joanne.youson@rs-components.com
+44 (0) 1536 405752

PR Agency Contact:

Janice Fenton

Account Director

Publitek Technology PR

janice.fenton@publitek.com

+44 (0) 1225 470000

Further information is available via these links:

Twitter: @RSComponents; @alliedelec; @designsparkRS

RS Components on Linkedin

http://www.linkedin.com/company/rs-components

 

Relevant Links:

Electrocomponents plc

www.electrocomponents.com

RS Components

www.rs-online.com

DesignSpark

http://www.designspark.com

 

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Life Sciences Supply Chain Benchmarking Survey 2015

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A 2015 LogiPharma Benchmarking Study (download here) reveals that 56% of pharma professionals think it is important to work with other pharma companies to develop a more effective supply chain.

logipharma2015The study, which was researched from October to November 2014, received over 50 responses. The report also revealed that only 30% of supply chain pharma professionals are very prepared and have all of processes and technologies in place for the global serialization requirements outlined in the EU Falsified Medicines Directive.

The goal of the survey was to gain insight from senior pharma supply chain professionals from across Europe and what their biggest priorities are for the next 12 months are.

When asked what the top 3 current challenges pharma professionals are facing, respondents answered with:

  • Balancing cost management versus providing excellent customer service
  • Managing the supply chain for a rapidly changing portfolio
  • Managing the supply chain

Download the report here

To see the other key findings as well as stats, facts and figures, you can download the full report here: http://wbresear.ch/oz

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Brian Yeardley hits high point as Krone Trailers deliver to new markets

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40th anniversary year sees ‘best ever’ results

Brian Yeardley Continental, the leading international transport and logistics operator, reports record business levels which, says the company include up to 100% growth in its chosen new market sector:  Exhibitions & Events Logistics.

841114 Krone - Brian Yeardley hits high point as Krone Trailers deliver to new markets (1) With its 40th anniversary approaching next year, Brian Yeardley expects to see a 10-15% uplift in its traditional European full load and Groupage business and expects to double  turnover in its new European Exhibition and Events Logistics division. Overall income has rocketed from circa £8m in 2010 to over £12m in 2014.The company’s heavy investment in its fleet during 2014 has included the recent addition of 20 Mega curtainsiders and 4 Mega box vans from Krone Trailers, which brings the total Krone compliment to 55. A reflection, the company says, of increased activity across its two core business sectors.

Specialist personnel with long experience in the event logistics industry have also joined the Yeardley team to bring first-hand knowledge and skills to the new division.

“As we move into our 40th year” comments Managing Director  Kevin Hopper “we continue to look for new markets and fresh opportunities – a policy which has underpinned our growth record over recent years and one which will see us go from strength to strength, here in the UK and in markets overseas.”

The 100 x m3 Krone Mega Box Liners are constructed from high strength insulated panels, which makes them ideal for handling high value and sensitive exhibition and event equipment. Twin decks can accommodate 52 standard or 66 euro pallets for general cargo and the double decks are ideal for steel deck, truss rigging and are set within a 22.500kg payload. The trailers’ stable inside temperature also makes them ideal for carrying IBCs and crated goods for the chemicals industry – a sector within which Yeardley is a major operator across Europe. 841114 Krone - Managing Director Kevin Hopper, Brian Yeardley Continental

For added security the Box Liners are fitted with Krone’s unique door locking system which is alarmed and fitted with a telematics monitoring device. To ensure maximum security and further load protection, the trailers are also equipped with stowable loading ramps for loading or unloading at events venues.

The mega curtainsiders or Profi Liner Mega trailers will be used for Yeardley’s general haulage and Groupage operations in the UK and Europe, while at the same time doubling up for the events division when needed. Also high volume, at 100 x m3, the curtainsiders feature Krone’s award-winning Multi Lock strapping system, which has up to 130 lashing points along each side rave. This enables virtually any sized load to be individually strapped, securely and safely anywhere along the trailer bed and is therefore ideal for mixed loads, including white goods and automotive parts – typical cargo for Yeardley’s international Groupage work.

For additional security and load protection, the curtains are reinforced with a steel, armour core which makes them anti-slash. All the trailers are built to code EN 12642-XL – the stringent European standard for vehicle body construction.

“From Barcelona to Berlin and Aberdeen to Amsterdam, at festivals and events throughout Europe, our customers not only require maximum volume, safe loading and reliability but also depend on the highest levels of load security,” adds Hopper, “We made this clear during the specification stage and Krone certainly delivered the right equipment for the job.”

Also about to join Yeardley’s 43  high profile truck fleet are two more Mercedes Benz Actros Euro 6 480 BHP Gigaspace LHD units. Half of Brian Yeardley’s fleet are now Mercedes and DAF Euro 6 – engined tractors, ensuring they are working to do everything they can to help the environment.

“This is going to be our best ever trading year in the company’s 40 year history” said Kevin Hopper “the opportunities are out there and we intend to take them. With a combination of premier transport equipment with quality systems and a first rate team of committed people, we have no doubt that our customers, both regional and global; will continue to receive the high standard of service which they expect from Brian Yeardley Continental.”

Established in 1975 and based in West Yorkshire, Brian Yeardley Continental provides full load and Groupage services, including Hazardous (ADR) goods, for both import and exports throughout the UK and Mainland Europe plus, the company now offers a pan European Exhibition & Events Logistics service.

Hopper concluded “Our new branding really does say it all as regards what we do, the places we go and the service we give our clients – “GOING FURTHER FOR YOU.”

KRONE TRAILERS UK
Peckfield Business Park
Phoenix Avenue
Micklefield
Leeds
LS25 4DY

Tel: +44 (0) 1132 878817
Fax: +44 (0) 1132 878819
E-Mail: trailers@krone-uk.com
Web: www.krone-trailer.com

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Helapet Pre-filled Syringe Transporters

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Helapet are pleased to introduce the rigid Syringe Transporter, ideal for the safe site transportation of hazardous drugs and other medical solutions in pre-filled syringes. The Polyethylene Terephthalate (PETG) thermoplastic housing, provides effective protection against impacts, whilst accommodating heat sealing as a measure of tamper evidence.

ST1005_1

Providing effective containment against potential syringe discharge, Helapet Syringe Transporters can accommodate 1ml to 5ml, and 30ml to 50ml syringes. Supporting infection prevention and cross contamination measures, the Helapet Syringe Transporter is a welcomed addition our range of clinical transportation devices.

Features

  • A rigid PETG Thermoplastic Housing that can accommodate tamper evident closure
  • Improved protection of pre-filled syringes during cold chain and site transit
  • Effective containment of hazardous solutions during possible accidental
  • discharge.
  • Sterile and non-sterile options available based on client preference

Helapet specification table

Read more about Helapet Syringe Transporters

Helapet Limited, Lister House, Blackburn Road, Houghton Regis, Bedfordshire, LU5 5BQ, England, UK

Tel: 0800 0 328 428 • Tel: +44 (0)1582 501 980 • Fax: +44 (0)1582 501 981

E-mail: sales@helapet.co.uk

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Blood Temp 10 at the AABB annual meeting & CTTXPO in Denver, Colorado

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Come see the Shockwatch Blood Temp 10 in action at the AABB annual meeting and CTTXPO in Denver, Colorado Monday, Oct. 14th, 1:30 pm booth 1654.  You can also hear about best practices keep your blood supply safe in our Learning Lab “Before Good Blood Goes Bad.”

Presentation overview:Timestrip Blood Temp 10

Heating, freezing and thawing all affect the viability of blood and blood products and components. Temperature monitoring is a vital step in maintaining the safety of the world’s blood supply, ensuring that blood already known to be safe, remains safe.

A case study will be shared during the presentation to show how temperature indicators not only help identify potentially heat damaged blood but also assist with identifying critical control points within your blood logistics cycle.

According to the WHO around 107 million blood donations are collected globally every year and it is generally accepted that 2% of blood may be discarded.  The use of suitable equipment and good management of blood cold chain are important means of minimizing losses and donated blood.

A lack of product data leads to an unpredictable blood cold chain, which will create an environment of guesswork, assumptions and inaccurate predictions when it comes time to make blood safety and cost-recovery related decisions.

The lack of accurate data due to a poorly designed temperature tracking system will force the disposal of unadulterated blood and create financial loss.  These results are very expensive consequences that can be overcome with the implementation of the Blood Temp 10.  Developing a system of bag level temperature monitoring will deliver the results required to effectively build and maintain predictable cold chain management, allow for a greater level of cost recovery and drive awareness throughout the blood cold chain.

Bacterial contamination of blood components is the most frequently reported cause of transfusion-related fatalities.  BT10 ensures that bacteria growth due to elevated temperatures has not compromised blood during storage, transportation and distribution     

Increase patient safety by confirming blood product is kept within the required conditions.  If unsafe temperature conditions occur the BT10 will give you an assurance to know that you’ve captured those issues prior to introducing unsafe blood to a patient.

Mainlining temperature control during storage and shipment is of extreme importance in order to uphold high standards of regulatory compliance.  There are many variables that will negatively affect the safety of your blood supply.  Blood Temp 10 will provide auditable proof that each individual blood bag has been maintained according to relevant regulations.

We invite you to learn more – leave us your contact information and we will schedule a time for you to come visit the booth for a live demonstration.

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Temperature-Sensitive Labels for Containers of RBCs

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I found an interesting article that compares three types of temperature sensitive label and a digital thermometer for the measurement blood bag temperatures and used for blood safety management – it’s a really useful item and well worth a read.

Temperature-sensitive labels are adhesive tags that display color changes at preset temperatures. There have been no studies of the suitability of this technology for measuring the temperature of blood components during transportation and storage. We used a digital thermometer to measure temperature in different locations inside containers of RBCs as they were allowed to warm to ambient temperatures following removal from refrigeration. We compared these temperature readings with those of 3 temperature-sensitive labels. These labels are marketed to alert transfusion services if the temperature of blood bags exceeds 10B0C, which is the maximum permissible by Food and Drug Administration and American Association of Blood Banks requirements for transporting RBCs. The contents of refrigerated RBC units changed from one homogeneous temperature to a range of temperatures when containers were allowed to warm (undisturbed) to ambient temperatures. Color changes of all 3 temperature-sensitive labels correlated more with core compared with surface temperatures of RBC units. These devices add an additional dimension of safety to the conventional 30-minute rule, which limits storage of blood components at ambient temperature to 30 minutes.

Read the full article here –  Temperature-Sensitive Labels for Containers of RBCs

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